KIT 抗体
Quick Overview for KIT 抗体 (ABIN2665946)
抗原
See all KIT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
品牌
- Ultra-LEAF™
-
纯化方法
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
-
过滤
- 0.2 μm filtered
-
内毒素水平
-
Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
-
亚型
- IgG2b kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
储存液
- Azide free
-
注意事项
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
-
储存条件
- 4 °C
-
储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
-
-
- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
-
别名
- CD117
-
背景
- CD117 is a 145 kD immunoglobulin superfamily member, also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.
-
途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
抗原
-